Clinical Oncology
Volume 18, Issue 2 , Pages 93-103, March 2006

Mathematical Modelling of Survival of Glioblastoma Patients Suggests a Role for Radiotherapy Dose Escalation and Predicts Poorer Outcome After Delay to Start Treatment

  • N.G. Burnet

      Affiliations

    • University of Cambridge, Department of Oncology, Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • Corresponding Author InformationAuthor for correspondence: Dr Neil G. Burnet, University of Cambridge Department of Oncology, Oncology Centre (Box 193), Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK. Tel: +44-1223-336800; Fax: +44-1223-763120.
  • ,
  • R. Jena

      Affiliations

    • University of Cambridge, Department of Oncology, Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
  • ,
  • S.J. Jefferies

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
  • ,
  • S.P. Stenning

      Affiliations

    • MRC Clinical Trials Unit, London, UK
  • ,
  • N.F. Kirkby

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • Fluids Research Centre, School of Engineering, University of Surrey, Guildford, Surrey, UK

Received 15 November 2004; received in revised form 17 August 2005; accepted 17 August 2005.

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PII: S0936-6555(05)00423-1

doi:10.1016/j.clon.2005.08.017

Clinical Oncology
Volume 18, Issue 2 , Pages 93-103, March 2006