Clinical Oncology
Volume 20, Issue 1 , Pages 69-75 , February 2008

Tissue Effects after Stereotactic Body Radiotherapy using Cyberknife for Patients with Abdominal Malignancies

  • J.S. Cupp

      Affiliations

    • Department of Pathology, Stanford University Medical Center, Stanford, CA, USA
    • ,
  • A.C. Koong

      Affiliations

    • Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA
    • ,
  • G.A. Fisher

      Affiliations

    • Department of Medical Oncology, Stanford University Medical Center, Stanford, CA, USA
    • ,
  • J.A. Norton

      Affiliations

    • Department of Surgery, Stanford University Medical Center, Stanford, CA, USA
    • ,
  • K.A. Goodman

      Affiliations

    • Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
    • Corresponding Author InformationAuthor for correspondence: K. A. Goodman, Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA. Tel: +1-212-639-3983; Fax: +1-212-639-8876.

Received 22 March 2007 ,Revised 17 July 2007 ,Accepted 20 August 2007.

References 

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  3. Coia LR, Myerson RJ, Tepper JE. Late effects of radiation therapy on the gastrointestinal tract. Int J Radiat Oncol Biol Phys. 1995;31:1213–1236
  4. Fajardo LF, Berthrong M, Anderson RE. Radiation pathology. 1st edn. New York: Oxford University Press; 2001;
  5. Fajardo LF. The pathology of ionizing radiation as defined by morphologic patterns. Acta Oncol. 2005;44:13–22
  6. Scemla R, Shah S, Schwartz M, et al. Colonic apple-core lesion resulting from Cyberknife treatment of unresectable pancreatic cancer. Pancreas. 2006;32:332–333
  7. Koong AC, Christofferson E, Le QT, et al. Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2005;63:320–323
  8. Hoyer M, Roed H, Sengelov L, et al. Phase-II study on stereotactic radiotherapy of locally advanced pancreatic carcinoma. Radiother Oncol. 2005;76:48–53
  9. Koong AC, Le QT, Ho A, et al. Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2004;58:1017–1021
  10. Goodman KA, Lieskovsky Y, Yang G, et al. Phase I dose escalation study of Cyberknife stereotactic radiosurgery for liver malignancies [Abstract]. Proceedings of 2006 Gastrointestinal Cancers Symposium, 26–28 January 2006, San Francisco.
  11. Woodruff KH, Castro JR, Quivey JM, et al. Postmortem examination of 22 pancreatic carcinoma patients treated with helium ion irradiation. Cancer. 1984;53:420–425
  12. Fuks Z, Kolesnick R. Engaging the vascular component of the tumor response. Cancer Cell. 2005;8:89–91
  13. Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science. 2003;300:115
  14. Schuller BW, Rogers AB, Cormier KS, et al. No significant endothelial apoptosis in the radiation-induced gastrointestinal syndrome. Int J Radiat Oncol Biol Phys. 2007;68:205–210

PII: S0936-6555(07)00779-0

doi: 10.1016/j.clon.2007.08.009

Clinical Oncology
Volume 20, Issue 1 , Pages 69-75 , February 2008

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