Clinical Oncology
Volume 20, Issue 10 , Page 769 , December 2008

The Importance of the Immune System in Reovirus Therapy

References 

  1. Comins C, Heinemann L, Harrington K, et al. Reovirus: viral therapy for cancer ‘as nature intended’. Clin Oncol (R Coll Radiol). 2008;20:548–554
  2. White CL, Twigger KR, Vidal L, et al. Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial. Gene Ther. 2008;15:911–920
  3. Errington F, White CL, Twigger KR, et al. Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma. Gene Ther. 2008;15:1257–1270
  4. Errington F, Steele L, Prestwich R, et al. Reovirus activates human dendritic cells to promote innate antitumor immunity. J Immunol. 2008;180:6018–6026
  5. Prestwich RJ, Errington F, Hatfield P, et al. The immune system – is it relevant to cancer development, progression and treatment?. Clin Oncol (R Coll Radiol). 2008;20:101–112
  6. Prestwich RJ, Errington F, Ilett EJ, et al. Tumor infection by oncolytic reovirus primes adaptive anti-tumor immunity. Clin Cancer Res, in press.

PII: S0936-6555(08)00349-X

doi: 10.1016/j.clon.2008.08.004

Clinical Oncology
Volume 20, Issue 10 , Page 769 , December 2008