Clinical Oncology
Volume 21, Issue 5 , Pages 371-375 , June 2009

The Challenge of Scoring Radiation-induced Lung Toxicity

Received 3 September 2008 ,Revised 22 December 2008 ,Accepted 28 January 2009.

References 

  1. Schild SE, McGinnis WL, Graham D, et al. Results of a phase I trial of concurrent chemotherapy and escalating doses of radiation for unresectable non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2006;65:1106–1111
  2. Miller KL, Shafman TD, Marks LB. A practical approach to pulmonary risk assessment in radiotherapy of lung cancer. Semin Radiat Oncol. 2004;14:298–307
  3. Available from: www.rtog.org/members/toxicity/late.html
  4. Graham M, Purdy J, Emammi B, et al. Clinical DVH analysis for pneumonitis after 3D treatment for NSCLC. Int J Radiat Oncol Biol Phys. 1999;45:323–329
  5. Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic radiation. Int J Radiat Oncol Biol Phys. 1991;21:109–122
  6. Liao Z, Wang X, Wei HH, et al. Analysis of clinical and dosimetric factors associated with radiation pneumonitis in patients with NSCLC treated with concurrent chemotherapy and 3D conformal radiotherapy. Int J Radiat Oncol Biol Phys. 2005;63(Suppl.):S41;[abstract 68]
  7. Marks LB, Munley MT, Bentel GC, et al. Physical and biological predictors of changes in whole lung function following thoracic irradiation. Int J Radiat Oncol Biol Phys. 1997;39:563–570
  8. Rancati T, Ceresoli GL, Gagliardi G, et al. Factors predicting radiation pneumonitis in lung cancer patients: a retrospective study. Radiother Oncol. 2003;67:275–283
  9. Seppenwoolde Y, Lebesque JW, de Jaeger K, et al. Comparing different NTCP models that predict the incidence of radiation pneumonitis. Int J Radiat Oncol Biol Phys. 2003;55:724
  10. Sunyach MP, Falchero L, Pommier P, et al. Prospective evaluation of early lung toxicity following three-dimensional conformal radiation therapy in NSCLC: preliminary results. Int J Radiat Oncol Biol Phys. 2000;48:459–463
  11. Faria S, Souhami L, Portelance L, et al. Absence of toxicity with hypofractionated 3-dimensional radiation therapy for inoperable, early stage non-small cell lung cancer. Radiat Oncol. 2006;1:42–50
  12. Marks LB, Yu X, Vujaskovic Z, et al. Radiation-induced lung injury. Semin Radiat Oncol. 2003;13:333–345
  13. Kocak Z, Evans ES, Zhou SM, et al. Challenges in defining radiation pneumonitis in patients with lung cancer. Int J Radiat Oncol Biol Phys. 2005;62:635–638
  14. Schild SE, Bogart JA. Innovations in the radiotherapy of non-small cell lung cancer. J Thorac Oncol. 2006;1:85–92
  15. Kwa SL, Lebesque JV, Theuws JC. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys. 1998;42:1–9
  16. Rodrigues G, Lock M, D'Souza D, Yu E, VanDyk J. Prediction of radiation pneumonitis by dose-volume histogram parameters in lung cancer — a systematic review. Radiother Oncol. 2004;71:127–138
  17. Rosen II, Fischer TA, Antolak JA, et al. Correlation between lung fibrosis and radiation therapy dose after concurrent radiation therapy and chemotherapy for limited small cell lung cancer. Radiology. 2001;221:614–622
  18. Yorke ED, Jackson A, Rosenzweig KE, et al. Dose-volume factors contributing to the incidence of radiation pneumonitis in non-small-cell lung cancer patients treated with three-dimensional conformal radiation therapy. Int J Radiat Oncol Biol Phys. 2002;54:329–339
  19. Yu X, Zhou S, Kahn D, et al. Predicting RT-induced pulmonary symptoms based on the dose to the superior vs inferior lung in patients irradiated for lung cancer. Int J Radiat Oncol Biol Phys. 2003;57:415S
  20. Hernando M, Marks LB, Bentel GC, et al. Radiation-induced pulmonary toxicity: a dose-volume histogram analysis in 201 patients with lung cancer. Int J Radiat Oncol Biol Phys. 2001;51:650–659

PII: S0936-6555(09)00050-8

doi: 10.1016/j.clon.2009.01.017

Clinical Oncology
Volume 21, Issue 5 , Pages 371-375 , June 2009