Clinical Oncology
Volume 21, Issue 6 , Pages 502-508 , August 2009

Efficacy of Photodynamic Therapy as a Treatment for Gorlin Syndrome-related Basal Cell Carcinomas

  • J. Loncaster

      Affiliations

    • Department of Clinical Oncology, Christie Hospital, Manchester, UK
    • Corresponding Author InformationAuthor for correspondence: J. Loncaster, Department of Clinical Oncology, Christie Hospital, Manchester M20 4BX, UK. Tel: +44-161-446-3678; Fax: +44-161-446-3334.
    • ,
  • R. Swindell

      Affiliations

    • Department of Medical Statistics, Christie Hospital, Manchester, UK
    • ,
  • F. Slevin

      Affiliations

    • Department of Medical Statistics, Christie Hospital, Manchester, UK
    • ,
  • L. Sheridan

      Affiliations

    • Department of Radiology, Christie Hospital, Manchester, UK
    • ,
  • D. Allan

      Affiliations

    • North Western Medical Physics, Christie Hospital, Manchester, UK
    • ,
  • E. Allan

      Affiliations

    • Department of Clinical Oncology, Christie Hospital, Manchester, UK

Received 19 October 2008 ,Revised 4 March 2009 ,Accepted 19 March 2009.

References 

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  10. Loncaster JA, Moore JV, Allan D, Allan E. An ultrasound analysis of the response of Gorlin syndrome-related and sporadic basal cell carcinomas to aminolaevulinic acid photodynamic therapy. Photodiagn Photodyn Ther. 2005;2:149–155
  11. Rhodes LE, de Rie MA, Leifsdottir R, et al. Five-year follow-up of a randomized prospective trial of methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Arch Dermatol. 2007;143(9):1131–1136
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  13. Madan V, Loncaster JA, Allan D, et al. Nodular basal cell carcinoma in Gorlin's syndrome treated with systemic photodynamic therapy and interstitial optical fiber diffuser laser. J Am Acad Dermatol. 2006;55:S86–S89
  14. Loncaster JA, Allan E. Photodynamic therapy in the management of a patient with Gorlin syndrome (naevoid basal cell carcinoma syndrome). Photodiagn Photodyn Ther. 2006;3:134–137
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  17. Doctoroff A, Oberlender SA, Purcell SM. Full-face carbon dioxide laser resurfacing in the management of a patient with the nevoid basal cell carcinoma syndrome. Dermatol Surg. 2003;29:1236–1240
  18. Stockfletch E, Ulrich C, Hauschild A, et al. Successful treatment of basal cell carcinomas in a nevoid basal cell carcinoma syndrome with topical 5% imiquimod. Eur J Dermatol. 2002;12:569–572
  19. Micali G, Lacarrubba F, Nasca MR, De Pasquale R. The use of imiquimod 5% cream for the treatment of basal cell carcinoma as observed in Gorlin's syndrome. Clin Exp Dermatol. 2003;28:19–23
  20. Ferreres JR, Macaya A, Jucgla A, et al. Hundreds of basal cell carcinomas in a Gorlin–Goltz syndrome patient cured with imiquimod 5% cream. J Eur Acad Dermatol Venereol. 2006;20:877–878
  21. Geisse J, Caro I, Lindholm J, et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from two phase 3, randomised vehicle-controlled studies. J Am Acad Dermatol. 2004;50:722–733
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  23. Oseroff A, Sheih S, Frawley N, et al. Treatment of diffuse basal cell carcinomas and basaloid follicular hamatomas in nevoid basal cell carcinoma syndrome by wide-area 5-aminolevulinic acid photodynamic therapy. Arch Dermatol. 2005;141:60–67
  24. Itkin A, Gilchrest BA. δ-Aminolevulinic acid and blue light photodynamic therapy for the treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome. Dermatol Surg. 2004;30:1054–1061
  25. Smucler R, Vlk M. Combination of Er:YAG laser and photodynamic therapy in the treatment of nodular basal cell carcinoma. Lasers Surg Med. 2008;40:153–158
  26. Whitaker I, Shokrollahi K, James W, Mishra A, Lohona P, Murison M. Combined CO2 laser with photodynamic therapy for the treatment of nodular basal cell carcinomas. Ann Plastic Surg. 2007;59:484–488

PII: S0936-6555(09)00107-1

doi: 10.1016/j.clon.2009.03.004

Clinical Oncology
Volume 21, Issue 6 , Pages 502-508 , August 2009

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