Clinical Oncology
Volume 21, Issue 9 , Pages 720-727 , November 2009

An Assessment of Action Levels in Imaging Strategies in Head and Neck Cancer using TomoTherapy. Are Our Margins Adequate in the Absence of Image Guidance?

  • F. Houghton

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • R.J. Benson

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • G.S.J. Tudor

      Affiliations

    • Medical Physics Department, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • J. Fairfoul

      Affiliations

    • Medical Physics Department, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • J. Gemmill

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • J.C. Dean

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • D.S. Routsis

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • S.J. Jefferies

      Affiliations

    • Oncology Centre, Addenbrooke's Hospital, Cambridge, UK
    • ,
  • N.G. Burnet

      Affiliations

    • University of Cambridge Department of Oncology, Oncology Centre, Addenbrooke's Hospital, Hills Road, Cambridge, UK
    • Corresponding Author InformationAuthor for correspondence: N. G. Burnet, University of Cambridge Department of Oncology, Oncology Centre (Box 193-R4), Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ, UK. Tel: +44-1223336800; Fax: +44-1223763120.

Received 25 January 2009 ,Revised 22 July 2009 ,Accepted 19 August 2009.

References 

  1. Chao KS, Deasy JO, Markman J, et al. A prospective study of salivary function sparing in patients with head and neck cancers receiving intensity-modulated or three dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys. 2001;49:907–916
  2. Hong TS, Tome WA, Chappell RJ, Chinnaiyan P, Mehta MP, Harari PM. The impact of daily set-up variations on head and neck intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2005;61:779–788
  3. de Boer HC, Heijmen BJ. A protocol for the reduction of systematic patient setup errors with minimal portal imaging workload. Int J Radiat Oncol Biol Phys. 2001;50:1350–1365
  4. Greener T. Appendix 2C. Geometric uncertainties in radiotherapy treatment planning. London: British Institute of Radiology; 2003;
  5. van Herk MP, Remeijer P, Rasch C, Lebesque JV. The probability of correct target dosage: dose-population histograms for deriving treatment margins in radiotherapy. Int J Radiat Oncol Biol Phys. 2000;47:1121–1135
  6. Bortfeld T, van Herk M, Jiang SB. When should systematic patient positioning errors in radiotherapy be corrected. Phys Med Biol. 2002;47(23):N297–N302
  7. Kupelian PA, Lee C, Langen KM, et al. Evaluation of image-guidance strategies in the treatment of localized prostate cancer. Int J Radiat Oncol Biol Phys. 2008;70(4):1151–1157
  8. Beldjoudi G, Yartsev S, Battista JJ, Van Dyk J. Optimisation du processus d'imagerie de haute énergie (MVCT) pour la tomothérapie hélicoïdale des cancers de la prostate. Cancer Radiother. 2008;12(5):316–322
  9. Humphreys M, Guerrero Urbano MT, Mubata C, et al. Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging. Radiother Oncol. 2005;77:39–44
  10. Zeidan OA, Langen KM, Meeks SL, et al. Evaluation of image-guidance protocols in the treatment of head and neck cancers. Int J Radiat Oncol Biol Phys. 2007;67:670–677
  11. Bentel GC, Marks LB, Hendren K, Brizel DM. Comparison of two head and neck immobilisation systems. Int J Radiat Oncol Biol Phys. 1997;38:867–873
  12. Gilbeau L, Octave-Prignot M, Loncol T, Renard L, Scalliet P, Gregoire V. Comparison of set-up accuracy of three different thermoplastic masks for the treatment of brain and head and neck tumours. Radiother Oncol. 2001;58:155–162
  13. Suzuki M, Nishimura Y, Nakamatsu K, et al. Analysis of interfractional set-up errors and intrafractional organ motions during IMRT for head and neck tumours to define an appropriate planning target volume (PTV) and planning organs at risk volume (PRV) margins. Radiother Oncol. 2006;78:283–290
  14. Schoenfield GO, Amdur RJ, Morris CG, Li JG, Hinerman RW, Mendenhall WM. Patterns of failure and toxicity after intensity modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 2008;71:377–385
  15. Stroom JC, Heijmen BJ. Limitations of the planning organ at risk volume (PRV) concept. Int J Radiat Oncol Biol Phys. 2006;66:279–286
  16. Nguyen TB, Hoole ACF, Burnet NG, Thomas SJ. Dose-volume population histogram: a new tool for evaluating plans whilst considering geometrical uncertainties. Phys Med Biol. 2009;54(4):935–947
  17. McKenzie A, van Herk M, Mijnheer . Margins for geometric uncertainty around organs at risk in radiotherapy. Radiother Oncol. 2002;62:299–307

PII: S0936-6555(09)00262-3

doi: 10.1016/j.clon.2009.08.005

Clinical Oncology
Volume 21, Issue 9 , Pages 720-727 , November 2009

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