Clinical Oncology
Volume 22, Issue 3 , Pages 173-178 , April 2010

The Application of Positron Emission Tomography/Computed Tomography in Radiation Treatment Planning: Effect on Gross Target Volume Definition and Treatment Management

  • Ş. İğdem

      Affiliations

    • Department of Radiation Oncology, İstanbul Bilim University, School of Medicine, Cemil Aslan Güder sok 8 Gayrettepe, 34340 İstanbul, Turkey
    • Corresponding Author InformationAuthor for correspondence: Ş. İğdem, Department of Radiation Oncology, İstanbul Bilim University, School of Medicine, Cemil Aslan Güder sok 8 Gayrettepe, 34340 Istanbul, Turkey. Tel: +90-212-3365570; Fax: +90-212-2882969.
  • ,
  • G. Alço

      Affiliations

    • Department of Radiation Oncology, Florence Nightingale Gayrettepe Hospital, İstanbul, Turkey
  • ,
  • T. Ercan

      Affiliations

    • Department of Radiation Oncology, Florence Nightingale Gayrettepe Hospital, İstanbul, Turkey
  • ,
  • B. Ünalan

      Affiliations

    • Department of Nuclear Medicine, Florence Nightingale Gayrettepe Hospital, İstanbul, Turkey
  • ,
  • B. Kara

      Affiliations

    • Department of Radiology, Florence Nightingale Şişli Hospital, İstanbul, Turkey
  • ,
  • G. Geceer

      Affiliations

    • Department of Radiology, Florence Nightingale Şişli Hospital, İstanbul, Turkey
  • ,
  • C. Akman

      Affiliations

    • Department of Radiology, Florence Nightingale Şişli Hospital, İstanbul, Turkey
  • ,
  • F.O. Zengin

      Affiliations

    • Department of Radiation Oncology, Florence Nightingale Gayrettepe Hospital, İstanbul, Turkey
  • ,
  • S. Atilla

      Affiliations

    • Department of Radiation Oncology, Florence Nightingale Gayrettepe Hospital, İstanbul, Turkey
  • ,
  • S. Okkan

      Affiliations

    • Department of Radiation Oncology, İstanbul Bilim University, School of Medicine, Cemil Aslan Güder sok 8 Gayrettepe, 34340 İstanbul, Turkey

Received 25 November 2009 ,Revised 21 December 2009 ,Accepted 23 December 2009.

References 

  1. van Herk M. Different styles of image guided radiotherapy. Semin Radiat Oncol. 2007;17:258–267
  2. Moran JM, Elshaikh MA, Lawrence TS. Radiotherapy: what can be achieved by technical improvements in dose delivery?. Lancet Oncol. 2005;6:51–58
  3. Webster GJ, Kilgallon JE, Ho KF, Rowbottom CG, Slevin NJ, Mackay RI. A novel imaging technique for fusion of high quality immobilised MR images of the head and neck with CT scans for radiotherapy target delineation. Br J Radiol. 2009;82:497–503
  4. Chen L, Price RA, Wang L, et al. MRI-based treatment planning for radiotherapy: dosimetric verification for prostate IMRT. Int J Radiat Oncol Biol Phys. 2004;60:636–647
  5. Rasch C, Steenbakkers R, van Herk M. Target definition in prostate, head, and neck. Semin Radiat Oncol. 2005;15:136–145
  6. Rohren EM, Turkington TG, Coleman RE. Clinical application of PET in oncology. Radiology. 2004;231:305–332
  7. Caldwell CB, Mah K, Ung YC, et al. Observer variation in contouring gross tumor volume in patients with poorly defined non-small-cell lung tumors on CT: the impact of 18FDG-hybrid PET fusion. Int J Radiat Oncol Biol Phys. 2001;51:923–931
  8. MacManus M, Nestle U, Rosenzweig KE, et al. Use of PET and PET/CT for radiation therapy planning: IAEA expert report 2006–2007. Radiother Oncol. 2009;91:85–94
  9. İğdem Ş, Okkan S, Ünalan B, İğdem A, Ferhanoğlu B. Cervical cancer coexisting with small lymphocytic lymphoma detected during positron emission tomography/computed tomography simulation: a case report. Eur J Gynaecol Oncol. 2008;4:405–407
  10. Schwartz DL, Ford E, Rajendran J, et al. FDG-PET/CT imaging for preradiotherapy staging of head and neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2005;61:129–136
  11. Gould MK, Kuschner WG, Rydzak CE, et al. Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non small cell lung cancer: a meta analysis. Ann Intern Med. 2003;139:879–892
  12. Reinhardt MJ, Ehritt-Braun C, Vogelgesang D, et al. Metastatic lymph nodes in patients with cervical cancer: detection with MR imaging and FDG PET. Radiology. 2001;218:776–782
  13. Ciernik F, Dizendorf E, Baumert BG, et al. Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study. Int J Radiat Oncol Biol Phys. 2003;57:853–863
  14. Daisne JF, Duprez T, Weynard B, et al. Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG-PET and validation with surgical specimen. Radiology. 2004;233:93–100
  15. Ahn PH, Garg MK. Positron emission tomography/computed tomography for target delineation in head and neck cancers. Semin Nucl Med. 2008;38:141–148
  16. Nestle U, Walter K, Schmidt S, et al. 18F-Deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis. Int J Radiat Oncol Biol Phys. 1999;44:593–597
  17. De Ruysscher D, Wanders S, van Haren E, et al. Selective mediastinal node irradiation based on FDG-PET scan data in patients with non small cell lung cancer: a prospective clinical study. Int J Radiat Oncol Biol Phys. 2005;62:988–994
  18. Gregoire V, Haustermans K, Geets X, Roels S, Lonneux M. PET-based treatment planning in radiotherapy: a new standard?. J Nucl Med. 2007;48:68S–77S
  19. Black QC, Grills IS, Kestin LL, et al. Defining a radiotherapy target with positron emission tomography. Int J Radiat Oncol Biol Phys. 2004;60:1272–1282
  20. Guido A, Fuccio L, Rombi B, et al. Combined 18F-FDG-PET/CT in radiotherapy target delineation for head and neck cancer. Int J Radiat Oncol Biol Phys. 2009;73:759–763
  21. Ashamalla H, Guirgius A, Bieniek E, et al. The impact of positron emission tomography/computed tomography in edge delineation of gross tumor volume for head and neck cancers. Int J Radiat Oncol Biol Phys. 2007;68:388–395
  22. Dizendorf EV, Baumert BG, von Schulthess GK, Lütolf UM, Steinert HC. Impact of whole body 18F-FDG PET on staging and managing patients for radiation therapy. J Nucl Med. 2003;44:24–29

PII: S0936-6555(10)00006-3

doi: 10.1016/j.clon.2010.01.003

Clinical Oncology
Volume 22, Issue 3 , Pages 173-178 , April 2010