Clinical Oncology
Volume 22, Issue 6 , Pages 456-463, August 2010

External Beam Radiotherapy for Differentiated Thyroid Cancer

  • C. Powell

      Affiliations

    • The Royal Marsden Hospital, London, UK
    • The Institute of Cancer Research, London, UK
    • ,
  • K. Newbold

      Affiliations

    • The Royal Marsden Hospital, London, UK
    • ,
  • K.J. Harrington

      Affiliations

    • The Royal Marsden Hospital, London, UK
    • The Institute of Cancer Research, London, UK
    • ,
  • S.A. Bhide

      Affiliations

    • The Royal Marsden Hospital, London, UK
    • The Institute of Cancer Research, London, UK
    • ,
  • C.M. Nutting

      Affiliations

    • The Royal Marsden Hospital, London, UK
    • The Institute of Cancer Research, London, UK
    • Corresponding Author InformationAuthor for correspondence: C.M. Nutting, Head and Neck Unit, The Royal Marsden Hospital, 207 Fulham Road, London SW3 6JJ, UK. Tel: +44-20-78082586; fax: +44-20-7808 2235.

Received 1 February 2010; accepted 22 March 2010. published online 28 April 2010.

Abstract 

The management of differentiated thyroid cancer involves a combination of surgery, thyroid stimulating hormone suppression and radioactive iodine for most patients. In a small subset of patients, external beam radiotherapy is also used. However, its role remains controversial and there are no randomised controlled trials to guide practice. In this overview we review the evidence from the published literature for the use of external beam radiotherapy in the management of differentiated thyroid cancer and discuss the indications for which it is most commonly used. The technique of external beam radiotherapy, including the emerging role for intensity-modulated radiotherapy, will also be discussed.

Key words: Differentiated thyroid cancer, external beam radiotherapy, intensity-modulated radiotherapy

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PII: S0936-6555(10)00124-X

doi:10.1016/j.clon.2010.03.012

Clinical Oncology
Volume 22, Issue 6 , Pages 456-463, August 2010

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