Clinical Oncology
Volume 22, Issue 6 , Pages 395-404, August 2010

Thyroid Cancer Epidemiology and Prognostic Variables

  • J.A. Sipos

      Affiliations

    • Division of Endocriniology, Ohio State University, Columbus, OH, USA
    • Corresponding Author InformationAuthor for correspondence: J.A. Sipos, 1581 Dodd Drive, Columbus, OH 43210, USA. Tel: +1 614 292 3800; Fax: +1 614 292 1550.
    • ,
  • E.L. Mazzaferri

      Affiliations

    • Division of Endocriniology, Ohio State University, Columbus, OH, USA
    • Division of Endocrinology, University of Florida, Gainesville, FL, USA

Received 4 February 2010; received in revised form 9 March 2010; accepted 4 May 2010. published online 04 June 2010.

Abstract 

Thyroid cancer comprises a broad spectrum of diseases with variable prognoses. Although most patients with this disease have excellent overall survival, there are some who do not fare so well. With the worldwide increase in incidence, the need to identify which tumours pose the greatest risk to patients is more acute than ever. This paper will discuss this rising trend in incidence with an analysis of the possible reasons for the increase. In addition, the paper will explore the factors that portend a worse prognosis for the individual patient. Finally, the limitations of the current staging systems will be discussed, with particular emphasis on why they are not as informative in the management of patients with thyroid cancer.

Key words: Differentiated thyroid cancer, epidemiology, pathogenesis of thyroid cancer

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PII: S0936-6555(10)00174-3

doi:10.1016/j.clon.2010.05.004

Clinical Oncology
Volume 22, Issue 6 , Pages 395-404, August 2010

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